Description

23(S)-Me-Udca is a high-purity, stereochemically defined derivative of ursodeoxycholic acid, a key bile acid. This compound is of significant interest in pharmaceutical research and development due to its potential as a reference standard and a synthetic intermediate for novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic, liver, and gastrointestinal drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical chiral building block in the synthetic pathways of advanced therapeutic compounds.
• Metabolic Pathway Research: Employed in biochemical studies to investigate bile acid metabolism, signaling, and related disorders.
• Drug Discovery & Development: Utilized in preclinical research for evaluating pharmacological activity, pharmacokinetics, and toxicity of new chemical entities targeting FXR and other nuclear receptors.
• Academic & Institutional Research: Applied in university and laboratory settings for fundamental studies in organic chemistry, stereochemistry, and medicinal chemistry.

Basic Information

Product Name	23(S)-Me-Udca
CAS No.	97883-85-7
Molecular Formula	C₂₅H₄₂O₄
Molecular Weight	406.60 g/mol
Synonyms	23(S)-Methylursodeoxycholic Acid; 3α,7β-Dihydroxy-23(S)-methyl-5β-cholan-24-oic Acid; 23-MethylUDCA; (23S)-Methylursodeoxycholic Acid; 23(S)-Me-UDCA; 23-Methyl-ursodeoxycholic acid; 23(S)-Methyl-UDCA
EINECS	Contact for details

Quality Control

Our 23(S)-Me-Udca is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (23S-isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.