Description

Dabsyl-L-Methionine is a high-purity, chromophoric derivative of the essential amino acid L-Methionine, specifically designed for advanced analytical applications. Its primary value lies in its role as a critical derivatization reagent for the sensitive detection and quantification of amino acids via high-performance liquid chromatography (HPLC). This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and food science industries who require precise amino acid analysis for product development, purity verification, and metabolic studies.

Application

• Amino Acid Analysis (HPLC): As a pre-column derivatization agent for the ultrasensitive UV or fluorescence detection of amino acids, including L-Methionine, in complex matrices.
• Pharmaceutical QC & R&D: For the precise quantification of amino acids in peptide and protein drug substances, raw materials, and finished formulations.
• Biotechnology Research: Used in metabolic profiling, cell culture media analysis, and protein hydrolysis studies to determine amino acid composition.
• Food & Nutraceutical Analysis: Employed to assay amino acid content and profile in dietary supplements, infant formula, and protein-rich food products.
• Clinical & Diagnostic Research: Facilitates the analysis of amino acids in physiological fluids for research into metabolic disorders.
• Method Development & Validation: Serves as a key reference standard for developing and validating robust analytical methods in compliance with ICH guidelines.

Basic Information

Product Name	Dabsyl-L-Methionine
CAS No.	97684-99-6
Molecular Formula	C18H22N4O4S2
Molecular Weight	422.52 g/mol
Synonyms	4-Dimethylaminoazobenzene-4'-sulfonyl-L-methionine; DABSYL-L-Methionine; Dabsyl Methionine; L-Methionine Dabsyl Derivative; Nα-(4-Dimethylaminoazobenzene-4'-sulfonyl)-L-methionine; DABSYL-L-MET; Dabsyl-Met-OH
EINECS	Contact for details

Quality Control

Our Dabsyl-L-Methionine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for sensitive analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.