Description

Benzo(A)Pyrene-3,6-Quinol Monoglucuronide is a crucial glucuronide conjugate metabolite of benzo[a]pyrene, a well-studied polycyclic aromatic hydrocarbon (PAH). This compound is of significant value in biochemical and toxicological research for understanding the metabolic pathways, detoxification mechanisms, and biomarker development associated with PAH exposure. It is primarily utilized by researchers and analytical laboratories in the fields of environmental science, occupational health, and pharmaceutical development.

Application

• Biomarker Reference Standard: Serves as an analytical standard for the quantification of benzo[a]pyrene metabolites in biological samples (e.g., urine, blood) for exposure assessment.
• Metabolic Pathway Studies: Used in in vitro and in vivo research to elucidate Phase II conjugation pathways of carcinogenic PAHs.
• Toxicology Research: Essential for investigating the detoxification, bioactivation, and excretion profiles of benzo[a]pyrene.
• Analytical Method Development: Employed as a calibrant or internal standard in HPLC, LC-MS, and GC-MS methods for high-sensitivity detection.
• Environmental Monitoring: Supports studies linking environmental PAH contamination to human biomonitoring data.
• Pharmaceutical R&D: Used in studies related to chemoprevention and the modulation of xenobiotic metabolism enzymes.

Basic Information

Product Name	Benzo(A)Pyrene-3,6-Quinol Monoglucuronide
CAS No.	97387-24-1
Molecular Formula	C26H24O9
Molecular Weight	480.47 g/mol
Synonyms	Benzo[a]pyrene-3,6-diol 6-Glucuronide; 3-Hydroxybenzo[a]pyrene 6-O-β-D-Glucuronide; BP-3,6-quinol monoglucuronide; 3,6-Dihydroxybenzo[a]pyrene 6-glucuronide; B[a]P-3,6-Quinol Glucuronide; Benzo(a)pyrene-3,6-quinol glucuronide; 6-(β-D-Glucopyranuronosyloxy)-3-hydroxybenzo[a]pyrene
EINECS	Contact for details

Quality Control

Every batch of Benzo(A)Pyrene-3,6-Quinol Monoglucuronide is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.