Description

Mono-6-o-(p-Toluenesulfonyl)-γ-Cyclodextrin is a key functionalized derivative of γ-cyclodextrin, where a single tosyl group is selectively introduced at the primary hydroxyl position, creating a versatile intermediate for further chemical synthesis. This precise modification is critical for developing advanced molecular encapsulation systems with tailored properties for research and industrial applications. It is primarily sought by pharmaceutical researchers, material scientists, and specialty chemical manufacturers working on drug delivery, chiral separation, and catalyst design.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor for synthesizing more complex cyclodextrin derivatives used in drug formulation and solubility enhancement.
• Chiral Stationary Phase Development: Used in the preparation of selective media for high-performance liquid chromatography (HPLC) to separate enantiomers.
• Supramolecular Chemistry & Catalyst Design: Acts as a building block for constructing host-guest complexes and enzyme-mimicking catalysts.
• Polymer & Material Science: Employed to create functionalized polymers and smart materials with specific molecular recognition capabilities.
• Analytical Reference Standard: Utilized as a high-purity standard in analytical methods development and quality control for cyclodextrin-based products.
• Cosmetic & Personal Care Ingredient Synthesis: A starting material for producing novel encapsulating agents for fragrances and active ingredients.

Basic Information

Product Name	Mono-6-o-(p-Toluenesulfonyl)-γ-Cyclodextrin
CAS No.	97227-33-3
Molecular Formula	C56H86O42S
Molecular Weight	1415.33 g/mol
Synonyms	6-O-(p-Tolylsulfonyl)-γ-cyclodextrin; 6-O-Tosyl-γ-cyclodextrin; γ-Cyclodextrin 6-mono-p-toluenesulfonate; Mono(6-O-p-toluenesulfonyl)-γ-cyclodextrin; 6-Mono-O-tosyl-γ-cyclodextrin; 6I-O-(4-Methylbenzenesulfonyl)-γ-cyclodextrin; γ-Cyclodextrin 6-mono-tosylate; Ts-γ-CD
EINECS	Contact for details

Quality Control

Our Mono-6-o-(p-Toluenesulfonyl)-γ-Cyclodextrin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.