Description

(4R,5S,26R)-4,5-Epoxy-4,5-Dihydro-16-Hydroxy-26-Methoxyikarugamycin is a structurally complex, semi-synthetic derivative of the natural product ikarugamycin, characterized by its epoxy and methoxy functional groups. This compound is valued in advanced research for its potent biological activity, serving as a critical reference standard and pharmacologically active scaffold in drug discovery. It is primarily sought by pharmaceutical R&D teams and academic institutions focused on developing novel anti-infective and anti-cancer agents.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis and screening of new therapeutic agents.
• Antibiotic Mechanism Studies: Investigation of its mode of action against resistant bacterial strains due to its structural relation to ikarugamycin.
• Oncology Research: Evaluation of cytotoxic and anti-proliferative properties against various cancer cell lines.
• Biochemical Pathway Analysis: Used as a specific probe to study cellular signaling and metabolic pathways.
• Academic & Institutional Research: Serves as a high-purity compound for chemical biology and medicinal chemistry projects.
• Analytical Standard: Provides a certified reference material for quality control and method validation in analytical laboratories.

Basic Information

Product Name	(4R,5S,26R)-4,5-Epoxy-4,5-Dihydro-16-Hydroxy-26-Methoxyikarugamycin
CAS No.	97009-33-1
Molecular Formula	C₃₂H₄₃NO₇
Molecular Weight	553.69 g/mol
Synonyms	4,5-Epoxy-4,5-dihydro-16-hydroxy-26-methoxyikarugamycin; 26-Methoxyikarugamycin derivative; Ikarugamycin, 4,5-epoxy-4,5-dihydro-16-hydroxy-26-methoxy-, (4R,5S,26R)-; 97009-33-1; 4,5-Epoxyikarugamycin analog; 16-Hydroxy-26-methoxyikarugamycin
EINECS	Contact for details

Quality Control

Our (4R,5S,26R)-4,5-Epoxy-4,5-Dihydro-16-Hydroxy-26-Methoxyikarugamycin is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term storage, keep at 2-8°C. The compound is light-sensitive and should be handled under inert atmosphere when appropriate to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.