Description

U-69593 CAS NO 96744-75-1 is a potent and selective κ-opioid receptor (KOR) agonist, a key pharmacological tool compound in neuroscience research. Its high selectivity makes it invaluable for studying the distinct physiological and behavioral effects mediated by the κ-opioid receptor pathway. This compound is essential for researchers and pharmaceutical developers in neuropharmacology, pain management, and substance abuse research, providing critical insights for potential therapeutic development.

Application

• Neuroscience Research: A standard tool for investigating the role of κ-opioid receptors in pain modulation, mood disorders, and stress responses.
• Pharmacological Studies: Used in in vitro and in vivo assays to characterize receptor binding affinity, selectivity, and functional activity.
• Drug Discovery & Development: Serves as a reference compound for screening and developing novel analgesics and neuropsychiatric therapeutics targeting the KOR.
• Behavioral Research: Applied in preclinical models to study addiction, depression, anxiety, and other behaviors linked to the κ-opioid system.
• Biochemical Pathway Analysis: Used to elucidate downstream signaling cascades and cellular effects activated by KOR agonism.

Basic Information

Product Name	U-69593
CAS No.	96744-75-1
Molecular Formula	C₂₄H₃₂ClNO₂
Molecular Weight	401.97 g/mol
Synonyms	(+)-U-69593; U69593; (5α,7α,8β)-(-)-N-Methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]benzeneacetamide; 3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide (isomer); Kappa opioid receptor agonist U-69593; (+)-U69593; Spiradoline analog
EINECS	Contact for details

Quality Control

Our U-69593 is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 standards, and our quality systems support research requiring reliable and well-characterized biochemical tools.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.