Description

5,5'-Bis(Trifluoromethyl)-3,3'-Dichloro-2H-1,2'-Bipyridin-2-One is a high-value, multi-functional heterocyclic compound distinguished by its unique trifluoromethyl and chloro substituents. This molecular architecture makes it a critical advanced intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors where its structural motifs are highly sought after. It is essential for researchers and process chemists in fine chemical and active pharmaceutical ingredient (API) development who require specialized building blocks to introduce specific functionalities and modulate the physical properties of target compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common pharmacophore.
• Material Science Research: Serves as a precursor for creating specialized ligands, catalysts, or monomers for advanced polymers with specific electronic or surface properties.
• Organic Synthesis & Process Chemistry: An important reagent for constructing complex bipyridine-based frameworks in academic and industrial R&D settings.
• Fluorinated Compound Library Development: Used by CROs and pharmaceutical companies to expand chemical libraries for high-throughput screening and drug discovery programs.

Basic Information

Product Name	5,5'-Bis(Trifluoromethyl)-3,3'-Dichloro-2H-1,2'-Bipyridin-2-One
CAS No.	96741-18-3
Molecular Formula	C₁₂H₄Cl₂F₆N₂O
Molecular Weight	377.07 g/mol
Synonyms	3,3'-Dichloro-5,5'-bis(trifluoromethyl)-2H,2'H-[1,2']bipyridinyl-2-one; 3,3'-Dichloro-5,5'-bis(trifluoromethyl)-2,2'-bipyridin-1(2H)-one; 5,5'-Bis(trifluoromethyl)-3,3'-dichloro-2,2'-bipyridin-1(2H)-one; 96741-18-3; Bipyridin-2-one, 5,5'-bis(trifluoromethyl)-3,3'-dichloro-2H-1,2'-
EINECS	Contact for details

Quality Control

Our production of 5,5'-Bis(Trifluoromethyl)-3,3'-Dichloro-2H-1,2'-Bipyridin-2-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.