Description

4-Fluoro-2-Methoxypyridine is a versatile fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in the synergistic reactivity of the fluorine atom and the methoxy group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine moiety enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its ability to fine-tune electronic properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic pathway studies and diagnostic agent development.

Basic Information

Product Name	4-Fluoro-2-Methoxypyridine
CAS No.	96530-81-3
Molecular Formula	C6H6FNO
Molecular Weight	127.11 g/mol
Synonyms	2-Methoxy-4-fluoropyridine; 4-Fluoro-2-methoxypyridine; 4-Fluoro-2-pyridinol methyl ether; 2-Pyridinol, 4-fluoro-, methyl ether; 4-Fluoro-2(1H)-pyridinone, O-methyl derivative
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.