Description

2-Hydroxy-4-Fluoropyridine is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the juxtaposition of hydroxyl and fluorine substituents on the pyridine ring, enabling precise molecular modifications. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Chemical Biology Probes: Utilized in designing molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	2-Hydroxy-4-Fluoropyridine
CAS No.	96530-75-5
Molecular Formula	C5H4FNO
Molecular Weight	113.09 g/mol
Synonyms	4-Fluoro-2-pyridinol; 4-Fluoro-2-hydroxypyridine; 2-Pyridinol, 4-fluoro-; 4-Fluoro-2(1H)-pyridinone; 2-Hydroxy-4-fluoropyridine; 4-Fluoropyridin-2-ol; 4-Fluoro-1H-pyridin-2-one
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-Fluoropyridine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.