Description

15(R)-15-Methyl Prostaglandin A2 is a synthetic methylated analog of prostaglandin A2, a key member of the cyclopentenone prostaglandin family. This compound is valued for its potent biological activity and serves as a crucial reference standard and research tool in biochemical and pharmacological studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for investigating cellular signaling pathways, inflammation, and metabolic regulation.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting inflammation, cancer, and metabolic disorders.
• Biochemical Research: A critical tool for studying the biological roles of cyclopentenone prostaglandins, including their effects on cell proliferation, apoptosis, and gene expression.
• Cell Signaling Studies: Employed to investigate PPARγ (Peroxisome Proliferator-Activated Receptor Gamma) activation and other nuclear receptor pathways in metabolic and inflammatory processes.
• Academic & Institutional Research: Serves as a key reagent in university and institutional labs for fundamental research in physiology, pharmacology, and medicinal chemistry.
• Analytical Standard: Used as a high-purity standard for method development, validation, and quality control in analytical laboratories (e.g., HPLC, LC-MS).

Basic Information

Product Name	15(R)-15-Methyl Prostaglandin A2
CAS No.	96440-68-5
Molecular Formula	C21H34O5
Molecular Weight	366.49 g/mol
Synonyms	15(R)-15-Methyl PGA2; 15-Methylprostaglandin A2; (5Z,13E)-(15R)-15-Methyl-9-oxoprosta-5,10,13-trien-1-oic acid; 15-Methyl-PGA2; Methyl PGA2; 15(R)-Methyl Prostaglandin A2; 15-Me-PGA2; 15(R)-15-Methylprostaglandin A2
EINECS	Contact for details

Quality Control

Our 15(R)-15-Methyl Prostaglandin A2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.