Description

Metaphit Methanesulfonate CAS NO 96316-00-6 is a specialized chemical compound widely utilized as a potent and irreversible ligand for the phencyclidine (PCP) binding site of the NMDA receptor complex. This high-purity intermediate is critical for advanced neuroscience research and pharmaceutical development, enabling the study of glutamate receptor function and neuroprotective mechanisms. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on central nervous system (CNS) drug discovery and neuropharmacology.

Application

• Neuroscience Research: As a key pharmacological tool for studying NMDA receptor subtypes, channel block kinetics, and allosteric modulation.
• Neuropharmacology: Used in the development and screening of novel neuroprotective agents, anticonvulsants, and analgesics targeting glutamate pathways.
• Biochemical Assays: Serves as a reference standard and active ligand in receptor binding assays and autoradiography studies.
• Pharmaceutical Intermediate: An important building block in the synthetic routes of experimental compounds designed to modulate excitatory neurotransmission.
• Toxicology Studies: Employed to model and investigate the mechanisms of excitotoxicity and related neurological disorders.

Basic Information

Product Name	Metaphit Methanesulfonate
CAS No.	96316-00-6
Molecular Formula	C11H14ClNO3S
Molecular Weight	275.75 g/mol
Synonyms	1-[1-(3-Isothiocyanatophenyl)cyclohexyl]piperidine Methanesulfonate; Metaphit; PCP isothiocyanate analog; NMDA receptor site ligand; 1-[1-(3-Isothiocyanatophenyl)cyclohexyl]piperidine mesylate; Metaphite; PCP site irreversible antagonist
EINECS	Contact for details

Quality Control

Our Metaphit Methanesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and research-grade materials, ensuring reliable performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.