Description

Pancratistatin CAS NO 96281-31-1 is a potent, naturally occurring isoquinoline alkaloid with significant biological activity. This compound is of high interest for its selective cytotoxic properties against various cancer cell lines, making it a valuable reference standard and research chemical. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in oncology drug discovery and development programs.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and lead compound in the discovery of novel anticancer therapeutics.
• Biochemical Assays: Used in in vitro studies to investigate mechanisms of apoptosis and cytotoxicity in cancer cell biology.
• Academic Research: Employed in university and institutional labs for pharmacological and chemical biology studies.
• Natural Product Chemistry: Acts as a benchmark compound for the isolation, synthesis, and structural analysis of related Amaryllidaceae alkaloids.
• Preclinical Studies: Utilized in animal model research to evaluate antitumor efficacy and pharmacokinetic profiles.

Basic Information

Product Name	Pancratistatin
CAS No.	96281-31-1
Molecular Formula	C₁₄H₁₅NO₈
Molecular Weight	325.27 g/mol
Synonyms	Pancratistatine; 1,2,3,4,4a,5,6,11b-Octahydro-9,10-dimethoxy-2,3-methylenedioxy-11bH-[1,3]dioxolo[4,5-j]phenanthridin-6-ol; Narciclasine analog; Amaryllidaceae alkaloid; 7-Deoxynarciclasine; Lycoricidine isomer
EINECS	Contact for details

Quality Control

Our Pancratistatin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research-grade chemicals to support the integrity of your scientific work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.