Description

6A-Carbaprostaglandin I3 is a synthetic analog of prostacyclin, a potent vasodilator and inhibitor of platelet aggregation. This compound is valued for its high biological activity and serves as a critical reference standard and research-grade intermediate in advanced pharmaceutical development. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on cardiovascular therapeutics, pulmonary hypertension, and novel anti-thrombotic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of related compounds in method development and validation.
• Biochemical Research: A key tool for studying prostacyclin (PGI2) receptor activity, signal transduction pathways, and vascular biology.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a high-purity building block in the synthesis of novel therapeutic agents targeting platelet aggregation and vasoconstriction.
• Cardiovascular Drug Discovery: Employed in preclinical research for developing new treatments for conditions like pulmonary arterial hypertension (PAH) and thrombosis.
• Cell Culture & In Vitro Studies: Used to investigate the cytoprotective and anti-proliferative effects of prostacyclin analogs on various cell types.

Basic Information

Product Name	6A-Carbaprostaglandin I3
CAS No.	96244-85-8
Molecular Formula	C₂₁H₃₂O₅
Molecular Weight	364.48 g/mol
Synonyms	6a-Carba-PGI3; 6a-Carbaprostaglandin I3; 6a-Carba-prostacyclin I3; 15-Cyclopentyl-ω-pentanor-5(E),13(E)-prostadienoic Acid; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-15-cyclopentyl-5,13-prostadienoic Acid
EINECS	Contact for details

Quality Control

Every batch of 6A-Carbaprostaglandin I3 is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.