Description

α-Fructoselysine Dihydrochloride is a chemically defined advanced glycation end-product (AGE) precursor, widely used as a critical reference standard and research reagent. This compound is essential for studying the Maillard reaction, protein glycation, and the biochemical pathways associated with diabetes and aging. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, diagnostic, and food science industries for method development, calibration, and analytical testing.

Application

• Biochemical Research: A key standard for investigating the formation and metabolism of advanced glycation end-products (AGEs) in metabolic disorders like diabetes.
• Diagnostic Kit Development: Used as a calibrant and reference material in the production of ELISA kits and other assays designed to measure glycated proteins or AGEs in biological samples.
• Pharmaceutical Analysis: Serves as a high-purity impurity standard and reference compound in the quality control of anti-diabetic drugs and related therapeutic agents.
• Food Science & Nutrition: Employed in studies to quantify and understand the formation of Maillard reaction products in processed foods, impacting flavor, color, and nutritional quality.
• Clinical Studies: Utilized as a biomarker precursor in research exploring the link between dietary AGEs, oxidative stress, and chronic diseases.
• Method Validation: Critical for developing and validating analytical methods such as HPLC, LC-MS/MS, and GC-MS for the accurate detection of glycation adducts.

Basic Information

Product Name	α-Fructoselysine Dihydrochloride
CAS No.	96192-34-6
Molecular Formula	C12H24N2O7 • 2HCl
Molecular Weight	381.25 g/mol
Synonyms	Fructoselysine Dihydrochloride; Nε-(1-Deoxy-1-fructosyl)lysine Dihydrochloride; N6-(1-Deoxyfructos-1-yl)-L-lysine Dihydrochloride; Amadori Product of Lysine; Lysine-Amadori Compound Dihydrochloride; 1-Deoxy-1-(N6-L-lysino)-D-fructose Dihydrochloride; AGE Precursor Standard
EINECS	Contact for details

Quality Control

Every batch of α-Fructoselysine Dihydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting requirements of research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.