Description

Azetirelin CAS NO 95729-65-0 is a synthetic peptide analog of thyrotropin-releasing hormone (TRH) with significant research and potential therapeutic applications. This compound is valued for its neuroprotective and neurotrophic properties, making it a critical material for advanced pharmaceutical development and neuroscience research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on central nervous system disorders, cognitive function, and neuroendocrine research.

Application

• Pharmaceutical R&D for the development of novel neuroprotective and nootropic agents.
• Neuroscience Research as a tool compound to study TRH receptor pathways and neurotrophic effects.
• Preclinical Studies investigating potential treatments for conditions like spinocerebellar degeneration, Alzheimer's disease, and other cognitive impairments.
• Reference Standard for analytical method development and quality control in peptide manufacturing.
• Biochemical Research to explore its effects on neurotransmitter release and neuronal excitability.
• Academic Research in neuropharmacology and neuroendocrinology departments worldwide.

Basic Information

Product Name	Azetirelin
CAS No.	95729-65-0
Molecular Formula	C16H23N7O4
Molecular Weight	377.40 g/mol
Synonyms	Azetireline; CG-3703; TA-0910; (S)-5-Oxopyrrolidine-2-carboxamide, N-[(4S,7S)-7-(2-amino-2-oxoethyl)-1-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanoyl]hexahydro-1H-1,4-diazepin-4-yl]carbonyl]-; Thyrotropin-Releasing Hormone Analog; TRH Analog; L-6-Ketopiperidine-2-carbonyl-L-histidyl-L-prolinamide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Azetirelin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and research needs with material produced to meet exacting standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.