Description

7,8-Dioxo-N,n-Didesmethylchlorpromazine is a key chemical intermediate and reference standard of significant interest in pharmaceutical research and development. This compound is valued for its role in the synthesis and analytical characterization of phenothiazine-derived compounds. It serves critical needs for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those focused on neuropharmacology and metabolite studies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced phenothiazine derivatives and related active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Metabolite Research: Employed in pharmacological and toxicological studies to investigate the metabolic pathways of chlorpromazine and analogous compounds.
• Biochemical Research: Utilized in studies exploring the interaction of phenothiazine derivatives with biological systems and enzymes.
• Organic Synthesis: Serves as a specialized starting material or reagent for the preparation of novel chemical entities in medicinal chemistry.

Basic Information

Product Name	7,8-Dioxo-N,n-Didesmethylchlorpromazine
CAS No.	95574-31-5
Molecular Formula	C17H15ClN2O2S
Molecular Weight	346.83 g/mol
Synonyms	7,8-Dioxo-N,N-didesmethylchlorpromazine; 2-Chloro-10-[3-(7,8-dioxo-7,8-dihydro-10H-phenothiazin-10-yl)propyl]-10H-phenothiazine-7,8-dione; Chlorpromazine Quinone Impurity; Didesmethylchlorpromazine Quinone; CPZ Quinone Metabolite
EINECS	Contact for details

Quality Control

Our 7,8-Dioxo-N,n-Didesmethylchlorpromazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.