Description

17-Debromo-2,3-Didehydro-3-Deoxy-31-Nor-4-Hydroxyaplysiatoxin is a structurally complex, bioactive marine natural product derivative, primarily valued for its role as a key reference standard and a versatile synthetic intermediate in advanced research. This compound is critical for scientists investigating protein kinase C (PKC) modulation, tumor promotion, and the structure-activity relationships of aplysiatoxin analogs. It is essential for pharmaceutical R&D, academic institutions, and biotechnology companies focused on oncology, dermatology, and chemical biology, where precise molecular tools are required for mechanism-of-action studies and novel therapeutic development.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for quality control and analytical method development in drug discovery pipelines.
• Biochemical Research: Serves as a critical tool compound for studying Protein Kinase C (PKC) activation, signaling pathways, and related biological mechanisms.
• Chemical Synthesis: Acts as a sophisticated synthetic intermediate or building block for the preparation of novel aplysiatoxin analogs and related bioactive molecules.
• Oncology Research: Utilized in in vitro and in vivo studies to explore tumor promotion, cell proliferation, and apoptosis, contributing to cancer biology understanding.
• Toxicology Studies: Employed as a model compound for investigating marine toxin effects and structure-toxicity relationships.
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry, natural product chemistry, and pharmacology at universities and research institutes.

Basic Information

Product Name	17-Debromo-2,3-Didehydro-3-Deoxy-31-Nor-4-Hydroxyaplysiatoxin
CAS No.	95098-07-0
Molecular Formula	C30H44O8
Molecular Weight	532.67 g/mol
Synonyms	31-Nor-4-Hydroxyaplysiatoxin; 17-Debromoaplysiatoxin derivative; 2,3-Didehydro-3-deoxy-31-nor-4-hydroxyaplysiatoxin; Debromoaplysiatoxin analog; Aplysiatoxin research compound; PKC activator derivative; Marine toxin intermediate; 95098-07-0
EINECS	Contact for details

Quality Control

Our 17-Debromo-2,3-Didehydro-3-Deoxy-31-Nor-4-Hydroxyaplysiatoxin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and custom synthesis and purification to specific customer specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.