Description

Calmidazolium is a potent and selective inhibitor of the calcium-binding protein calmodulin, playing a crucial role in modulating intracellular calcium signaling pathways. This high-purity compound is essential for advanced biochemical and pharmacological research, enabling the study of calcium-mediated cellular processes. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for drug discovery, target validation, and mechanistic studies.

Application

• Biochemical Research: A key tool for investigating the role of calmodulin in enzyme regulation, cell cycle progression, and signal transduction.
• Pharmaceutical R&D: Used in high-throughput screening and target validation for developing novel therapeutics targeting calcium signaling disorders.
• Neuropharmacology Studies: Employed to study calcium/calmodulin-dependent processes in neurons, relevant to neurological diseases.
• Cardiovascular Research: Applied in models to understand calmodulin's function in muscle contraction and cardiovascular physiology.
• Cell Biology: Utilized to dissect intracellular signaling cascades and second messenger systems in various cell types.
• Academic Research: A standard reagent in university and institutional labs for fundamental studies in molecular and cellular biology.

Basic Information

Product Name	Calmidazolium
CAS No.	95013-41-5
Molecular Formula	C₂₀H₂₂ClN₃O
Molecular Weight	355.86 g/mol
Synonyms	Calmidazolium Chloride; R 24571; R24571; 1-[Bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazolium Chloride; R-24571; NSC 326223; Calmidazolium chloride (R24571)
EINECS	Contact for details

Quality Control

Our Calmidazolium is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be provided to meet specific research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.