Description

3-Acetyl-6-Deoxy-6-Fluoronaltrexone is a chemically modified derivative of naltrexone, a well-known opioid antagonist. This compound is of significant interest in pharmaceutical research and development, particularly for creating novel therapeutic agents and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, medicinal chemistry, and the development of treatments for substance use disorders.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new opioid receptor antagonists and modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the effects of fluorination and acetylation on receptor binding affinity and pharmacokinetics.
• Neuroscience Research: Employed as a biochemical tool to study opioid receptor pathways and mechanisms in preclinical models.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Drug Discovery Programs: Integrated into screening libraries for identifying and optimizing new candidates targeting the central nervous system.

Basic Information

Product Name	3-Acetyl-6-Deoxy-6-Fluoronaltrexone
CAS No.	94696-53-4
Molecular Formula	C22H24FNO4
Molecular Weight	385.43 g/mol
Synonyms	6-Fluoro-6-deoxy-3-acetylnatrexone; 6-Fluoro-3-acetylnatrexone; 3-O-Acetyl-6-deoxy-6-fluoronaltrexone; 6-Fluoro-3-O-acetylnatrexone; 6-Fluoro-6-desoxynaltrexone 3-acetate; Naltrexone 3-acetate, 6-fluoro-6-deoxy-; 6-Fluoro-6-deoxy-3-O-acetylnatrexone
EINECS	Contact for details

Quality Control

Our 3-Acetyl-6-Deoxy-6-Fluoronaltrexone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards to support our clients in pharmaceutical R&D and analytical testing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.