Description

2-Fluorobenzoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in introducing the 2-fluorobenzoyl moiety, a key structural feature that can modulate the biological activity, metabolic stability, and physicochemical properties of target molecules. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and material science industries, where precise chemical functionality is paramount.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated compounds for enhanced drug efficacy and stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom improves biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Employed in the synthesis of fluorinated aromatic cores for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a grafting or coupling agent to introduce fluorinated benzoyl groups into polymer chains, altering surface properties and chemical resistance.
• Dye & Pigment Manufacturing: Serves as an intermediate for creating specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorinated compounds and reaction pathways.

Basic Information

Item	Detail
Product Name	2-Fluorobenzoyl Chloride
CAS No.	393-52-2
Molecular Formula	C7H4ClFO
Molecular Weight	158.56 g/mol
Synonyms	o-Fluorobenzoyl Chloride; 2-Fluorobenzoic Acid Chloride; 2-Fluorobenzenecarbonyl Chloride; o-Fluorobenzoic Acid Chloride; 2-Fluorobenzoyl Chloride; Fluorobenzoyl Chloride (unspecified isomer); Benzoic acid, 2-fluoro-, chloride
EINECS	206-886-0

Quality Control

Our 2-Fluorobenzoyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.