Description

1,3,5-Tris(trifluoromethyl)benzene is a highly fluorinated aromatic compound distinguished by its three symmetrically positioned trifluoromethyl groups. This unique structure imparts exceptional chemical stability, lipophilicity, and electron-withdrawing properties, making it a versatile and valuable building block in advanced chemical synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key synthon for creating drug candidates with enhanced metabolic stability and bioavailability, particularly in medicinal chemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a backbone for synthesizing sophisticated ligands used in catalysis and material science.
• Specialty Polymers & Materials: Incorporated into polymers to impart unique properties such as chemical resistance, low surface energy, and thermal stability for coatings and electronic materials.
• Organic Electronics: Acts as an electron-deficient moiety in the development of organic semiconductors and light-emitting materials.
• Fluorinated Liquid Crystals: A critical component in the synthesis of high-performance liquid crystal mixtures for display technologies.

Basic Information

Item	Details
Product Name	1,3,5-Tris(trifluoromethyl)benzene
CAS No.	729-81-7
Molecular Formula	C9H3F9
Molecular Weight	276.11 g/mol
Synonyms	1,3,5-Tris(trifluoromethyl)benzene; Benzene, 1,3,5-tris(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-1,3,5-trimethylbenzene; Trifluoromethylbenzene, 1,3,5-tris-; sym-Tris(trifluoromethyl)benzene; 1,3,5-(CF3)3C6H3; Perfluoro-1,3,5-trimethylbenzene (common name)
EINECS	211-981-5

Quality Control

Our 1,3,5-Tris(trifluoromethyl)benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency that meets the stringent requirements of advanced R&D and scale-up production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.