Description

2-Fluoro-1H-Imidazole Hydrochloride is a high-purity fluorinated heterocyclic building block essential for advanced pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the introduction of fluorine atoms to modulate biological activity and metabolic stability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the fluorine moiety enhances efficacy and environmental persistence.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and enzyme inhibitors to study biological pathways.
• Material Science Research: Serves as a precursor for novel fluorinated ionic liquids, ligands, or functional polymers with specialized properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting custom synthesis and scale-up projects for global clients.

Basic Information

Product Name	2-Fluoro-1H-Imidazole Hydrochloride
CAS No.	42309-92-2
Molecular Formula	C3H4FN2•HCl
Molecular Weight	122.53 g/mol (Free base: 86.07 g/mol)
Synonyms	2-Fluoroimidazole Hydrochloride; 2-Fluoro-1H-imidazole HCl; 1H-Imidazole, 2-fluoro-, hydrochloride; 2-Fluoroglyoxaline Hydrochloride; 2-F-Im HCl; 2-Fluoroimidazole monohydrochloride; 2-Fluorimidazolium chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-1H-Imidazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under dry conditions to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.