Description

(Chlorodifluoromethoxy)Benzene is a specialized fluorinated aromatic ether compound. This chemical serves as a versatile building block and intermediate in advanced organic synthesis, valued for its unique reactivity imparted by the chlorodifluoromethoxy group. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for creating novel molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated ether moieties to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoromethoxy group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving chemical resistance, lowering surface energy, and enhancing thermal stability.
• Organic Synthesis Reagent: Acts as an electrophile or a protecting group precursor in complex multi-step synthetic routes within R&D laboratories.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing novel aromatic compounds with specific olfactory characteristics.

Basic Information

Product Name	(Chlorodifluoromethoxy)Benzene
CAS No.	770-11-6
Molecular Formula	C7H5ClF2O
Molecular Weight	178.56 g/mol
Synonyms	Benzene, (chlorodifluoromethoxy)-; α,α-Difluoro-α-chloroanisole; Chlorodifluoromethoxybenzene; (Chlorodifluoromethoxy)benzene; 1-(Chlorodifluoromethoxy)benzene; Phenyl chlorodifluoromethyl ether; Difluorochloromethoxybenzene
EINECS	212-224-7

Quality Control

Our (Chlorodifluoromethoxy)Benzene is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.3 g/mL
Boiling Point	~180-185°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.