Description

9,21-Dehydroryanodine is a high-purity, structurally defined ryanodine derivative with the CAS number 94513-55-0. This compound is a critical reference standard and research-grade biochemical for investigating calcium signaling pathways and ion channel modulation. It is essential for researchers and developers in the pharmaceutical, agrochemical, and life sciences sectors who require precise tools for studying ryanodine receptor (RyR) function and developing novel therapeutic or crop protection agents.

Application

• Pharmacological Research: A key reference standard for studying the binding and functional modulation of ryanodine receptors (RyRs) in cardiac and skeletal muscle tissues.
• Neurobiology Studies: Used in neuroscience research to investigate calcium-induced calcium release (CICR) mechanisms and neuronal excitability.
• Agrochemical Development: Serves as a lead compound or biochemical probe in the research and development of novel insecticides targeting insect ryanodine receptors.
• Toxicology & Safety Assessment: Employed as an analytical standard in metabolic and toxicokinetic studies of ryanodine-related compounds.
• Biochemical Assay Development: Utilized in the development and validation of high-throughput screening (HTS) assays for drug discovery targeting calcium channels.
• Academic Research: A fundamental tool for universities and research institutes exploring cellular calcium homeostasis and signal transduction.

Basic Information

Product Name	9,21-Dehydroryanodine
CAS No.	94513-55-0
Molecular Formula	C₂₅H₃₅NO₈
Molecular Weight	477.55 g/mol
Synonyms	9,21-Dehydroryanodine; 9,21-Didehydroryanodine; Dehydroryanodine; Ryanodine derivative; (1R,2R,3S,6S,7S,8S,9S,11R,12S,15S)-6-(1H-Pyrrol-2-yl)-2,3,7,8,9,11,12,15-octahydro-1H-4,10-methenopyrano[3,2-g]azacycloundecine-1,3,7,8,9,11,12,15-octol; 9,21-Anhydroryanodine
EINECS	Contact for details

Quality Control

Our 9,21-Dehydroryanodine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (NMR, IR, MS), and residual solvent analysis, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.