Description

4-Chloro-2-Fluorobenzotrifluoride is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on a trifluoromethylated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Functional Material Development: Building block for polymers and advanced materials requiring specific electronic or surface properties.
• Organic Synthesis Research: Employed in academic and industrial R&D for cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce the benzotrifluoride moiety.

Basic Information

Product Name	4-Chloro-2-Fluorobenzotrifluoride
CAS No.	94444-59-4
Molecular Formula	C7H3ClF4
Molecular Weight	198.55 g/mol
Synonyms	2-Fluoro-4-chlorobenzotrifluoride; 4-Chloro-2-fluoro-α,α,α-trifluorotoluene; 1-Chloro-3-fluoro-4-(trifluoromethyl)benzene; 4-Chloro-2-fluoro-1-(trifluoromethyl)benzene; 2-Fluoro-4-chloro-α,α,α-trifluorotoluene; 4-Chloro-2-fluorobenzylidene trifluoride; (4-Chloro-2-fluorophenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluorobenzotrifluoride is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.48 g/cm³
Boiling Point	~165-170°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.