Description

10(R,S)-Hydroxy-11(S),12(S)-trans-Epoxyeicosa-5Z,8Z,14Z-Trienoic Acid is a specialized eicosanoid derivative, a key intermediate in the study of lipoxygenase and cytochrome P450 metabolic pathways. This compound matters for its role as a precursor in the biosynthesis of bioactive lipid mediators, which are critical for understanding inflammatory and vascular processes. It is primarily needed by research institutions and pharmaceutical companies engaged in metabolic research, drug discovery, and the development of analytical standards.

Application

• Biochemical Research: Used as a reference standard and intermediate in the study of arachidonic acid metabolism and eicosanoid biosynthesis pathways.
• Pharmaceutical Development: Serves as a key building block or metabolite analog in the discovery of novel anti-inflammatory and cardiovascular therapeutic agents.
• Analytical Chemistry: Employed as a high-purity standard for method development and validation in LC-MS, HPLC, and GC-MS analyses within metabolomics and lipidomics.
• Enzyme Studies: Acts as a substrate or inhibitor in assays for lipoxygenase (LOX) and cytochrome P450 (CYP) enzyme activity and kinetics.
• Cell Signaling Research: Investigated for its potential role and effects in cellular signaling cascades related to inflammation and immune response.

Basic Information

Item	Detail
Product Name	10(R,S)-Hydroxy-11(S),12(S)-trans-Epoxyeicosa-5Z,8Z,14Z-Trienoic Acid
CAS No.	94161-10-1
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	10-Hydroxy-11,12-epoxyeicosatrienoic acid; 10-HETrE; 10(R,S)-HETrE; 10-Hydroxy-11,12-epoxy-5Z,8Z,14Z-eicosatrienoic acid; 10-Hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoic acid; (±)-10-Hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoic acid; 10-Hydroxy-11,12-epoxy-5,8,14-eicosatrienoic acid
EINECS	Contact for details

Quality Control

Our 10(R,S)-Hydroxy-11(S),12(S)-trans-Epoxyeicosa-5Z,8Z,14Z-Trienoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and stability. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.