Description

Cicaprost CAS NO 94079-80-8 is a stable prostacyclin (PGI2) analog, a potent vasodilator and inhibitor of platelet aggregation. This compound is a critical research chemical and pharmaceutical intermediate for developing cardiovascular and pulmonary therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced cardiovascular drugs targeting hypertension and thrombosis.
• Biochemical Research: Used as a reference standard and tool compound in studies of prostacyclin receptors, vascular biology, and platelet function.
• Pulmonary Hypertension Research: Investigated for its potential in developing treatments for pulmonary arterial hypertension (PAH) due to its vasodilatory properties.
• Cell Culture & In Vitro Studies: Employed in cell-based assays to study cytoprotective effects and cellular signaling pathways.
• API Development: Serves as a precursor in the commercial-scale manufacturing of prostacyclin-based active pharmaceutical ingredients.

Basic Information

Product Name	Cicaprost
CAS No.	94079-80-8
Molecular Formula	C₂₃H₃₂O₅
Molecular Weight	388.50 g/mol
Synonyms	Cicaprost; ZK 96480; 5-[(1R,2R,3aS,9aS)-2-[(2E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-1-yl]pentanoic Acid; Iloprost Impurity C; Prostacyclin Analog ZK96480; (1R,2R,3aS,9aS)-2-[(2E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-1-ylpentanoic Acid
EINECS	Contact for details

Quality Control

Our Cicaprost is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.