Description

Suplatast Tosilate is a selective Th2 cytokine inhibitor with significant anti-allergic and anti-inflammatory properties. This compound is a key pharmaceutical intermediate and active ingredient, valued for its targeted mechanism of action in modulating immune responses. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of treatments for allergic disorders such as asthma, atopic dermatitis, and allergic rhinitis.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of anti-allergic and anti-asthmatic medications.
• Research & Development: Critical reference standard and building block in immunological and pharmacological studies targeting Th2-mediated diseases.
• Preclinical & Clinical Studies: Used in the development and validation of new therapeutic agents for allergic conditions.
• Intermediate Synthesis: Serves as a crucial precursor in the multi-step synthesis of more complex pharmaceutical compounds.
• Biochemical Research: Tool compound for investigating cytokine signaling pathways and immune cell function.

Basic Information

Product Name	Suplatast Tosilate
CAS No.	94055-76-2
Molecular Formula	C₂₃H₂₅NO₇S
Molecular Weight	459.51 g/mol
Synonyms	Suplatast Tosylate; (+)-Suplatast Tosilate; IPD-1151T; (S)-Suplatast Tosilate; 4-[(4-(3-Ethoxy-2-hydroxypropoxy)phenyl)amino]-3,4-dioxobut-1-en-2-ol p-Toluenesulfonate; Suplatast p-Toluenesulfonate; Suplatast Tosylate Salt
EINECS	Contact for details

Quality Control

Our Suplatast Tosilate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and residual solvent analysis, to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.