Description

Deltibant CAS NO 140661-97-8 is a synthetic peptide antagonist of the bradykinin B2 receptor. This compound is of significant interest in pharmaceutical research and development due to its specific mechanism of action. It is primarily utilized by research institutions and pharmaceutical companies engaged in the study of inflammation, pain pathways, and cardiovascular disorders.

Application

• Pharmacological Research: As a selective B2 receptor antagonist for investigating the role of bradykinin in inflammatory and pain responses.
• Drug Discovery: Serving as a reference standard or lead compound in the development of novel anti-inflammatory or analgesic therapeutics.
• Biochemical Assays: Used in in vitro and in vivo studies to elucidate bradykinin-mediated signaling pathways.
• Academic Research: A critical tool for universities and laboratories studying cardiovascular biology, neurogenic inflammation, and angioedema.
• Preclinical Development: Evaluation of efficacy and safety profiles in animal models for potential clinical applications.

Basic Information

Product Name	Deltibant
CAS No.	140661-97-8
Molecular Formula	C82H122N24O19S2
Molecular Weight	1724.1 g/mol
Synonyms	D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg; HOE 140; Icatibant; B2 Receptor Antagonist; Bradykinin B2 Antagonist; FR 173657; JE 049; B-9430
EINECS	Contact for details

Quality Control

Our Deltibant is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and tests for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 15.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.