Description

Ramatroban is a potent and selective thromboxane A2 receptor antagonist, a compound of significant interest in pharmaceutical research and development. Its primary value lies in its ability to modulate platelet aggregation and bronchoconstriction pathways, making it a key candidate for investigating treatments for allergic and inflammatory conditions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing novel therapeutics for asthma, allergic rhinitis, and related cardiovascular research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs) for clinical research.
• Biomedical Research: Used as a reference standard and tool compound in preclinical studies to investigate thromboxane-mediated pathways.
• Drug Discovery: Employed in high-throughput screening and mechanism-of-action studies for new anti-inflammatory and anti-allergic drug candidates.
• Academic Research: Utilized in university and institutional labs for pharmacological studies related to respiratory and cardiovascular systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	Ramatroban
CAS No.	116649-85-5
Molecular Formula	C21H25NO4S
Molecular Weight	387.49 g/mol
Synonyms	BAY u 3405; Ramatroban (BAYu3405); 3-[(4-Fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic Acid; BAY-u-3405; BAY-u3405; BAYu3405; BAY-u 3405
EINECS	Contact for details

Quality Control

Our Ramatroban is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development projects requiring material that aligns with ICH guidelines and cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.