Description

Ramatroban is a potent and selective thromboxane A2 receptor antagonist, a compound of significant interest in pharmacological research and development. Its primary value lies in its ability to modulate platelet aggregation and bronchoconstriction pathways, making it a key molecule for studying cardiovascular and respiratory conditions. This high-purity material is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on inflammation, thrombosis, and allergy research.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anti-thrombotic and anti-inflammatory therapeutics.
• Mechanistic Studies: Used extensively in in vitro and in vivo studies to investigate the role of thromboxane A2 receptors in platelet activation, smooth muscle contraction, and inflammatory responses.
• Biochemical Assay Development: Employed as a ligand in receptor binding assays and high-throughput screening (HTS) platforms to discover new receptor modulators.
• Academic Research: A vital tool for universities and research institutes studying cardiovascular diseases, asthma, allergic disorders, and related signal transduction pathways.
• Quality Control & Analytical Testing: Used as a certified reference material (CRM) for method validation, impurity profiling, and ensuring batch-to-batch consistency in API manufacturing.

Basic Information

Product Name	Ramatroban
CAS No.	141281-95-0
Molecular Formula	C21H25NO4S
Molecular Weight	387.49 g/mol
Synonyms	BAY u 3405; Ramatroban (BAYu3405); 3-[(4-Fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic Acid; BAY-u-3405; BAY u3405; BAYu3405; (3R)-3-[(4-Fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic Acid
EINECS	Contact for details

Quality Control

Our Ramatroban CAS NO 141281-95-0 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.