Description

1-(2-Bromoethyl)-2-(Trifluoromethyl)Benzene is a versatile aromatic building block featuring both a reactive bromoethyl side chain and a stable trifluoromethyl group. This combination makes it a critical intermediate for the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical sectors for constructing novel compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in organometallic chemistry.
• Fluorine Chemistry Research: A valuable substrate for studying the introduction and behavior of fluorinated motifs in organic molecules.
• Polymer Modification: Can be incorporated into polymer backbones to alter thermal stability, solubility, and chemical resistance.

Basic Information

Product Name	1-(2-Bromoethyl)-2-(Trifluoromethyl)Benzene
CAS No.	94022-95-4
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	2-(2-Bromoethyl)benzotrifluoride; α-Bromo-2-(trifluoromethyl)phenethylane; 2-(Trifluoromethyl)phenethyl Bromide; 1-Bromo-2-[2-(trifluoromethyl)phenyl]ethane; o-Trifluoromethylphenethyl Bromide; (2-Bromoethyl)(2-trifluoromethyl)benzene; 2-(2-Bromoethyl)benzene, 1-(trifluoromethyl)-; 94022-95-4
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Bromoethyl)-2-(Trifluoromethyl)Benzene is produced and tested under strict quality management systems. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as verified by GC, HPLC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.