Description

19-Hydroxy-16,16-Dimethylprostaglandin E2 is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound matters for its role in the synthesis of more complex prostaglandin derivatives, which are critical for studying and modulating biological pathways related to inflammation, smooth muscle contraction, and cellular signaling. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and academic institutions focused on developing novel therapeutic agents and conducting cutting-edge biochemical research.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel prostaglandin-based drug candidates targeting various therapeutic areas.
• Biochemical Research: Used as a reference standard and active agent in studies investigating prostaglandin receptor function, signal transduction, and metabolic pathways.
• Cell Culture & In Vitro Studies: Applied in controlled experiments to study its effects on cell proliferation, differentiation, and inflammatory responses.
• Method Development: Serves as a standard for developing and validating analytical methods (e.g., HPLC, LC-MS) for prostaglandin quantification in complex matrices.

Basic Information

Product Name	19-Hydroxy-16,16-Dimethylprostaglandin E2
CAS No.	93800-35-2
Molecular Formula	C24H40O6
Molecular Weight	424.58 g/mol
Synonyms	16,16-Dimethyl-19-hydroxy-PGE2; 19-Hydroxy-16,16-dimethyl-PGE2; 9-Oxo-11α,15S-dihydroxy-16,16-dimethyl-19-hydroxy-prosta-5Z,13E-dien-1-oic acid; 19-Hydroxy-16,16-dimethylprostaglandin E2; DM-19-OH-PGE2; 16,16-Dimethyl-19-hydroxyprostaglandin E2
EINECS	Contact for details

Quality Control

Our 19-Hydroxy-16,16-Dimethylprostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.