Description

4-Trifluoromethyl-β-Nitrostyrene CAS NO 93628-97-8 is a versatile fluorinated organic intermediate characterized by its reactive nitrostyrene and trifluoromethyl functional groups. This compound is critical for introducing the trifluoromethyl moiety into complex molecules, a modification known to significantly enhance metabolic stability, lipophilicity, and bioavailability in active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated monomers and polymers with unique optical, electronic, or surface properties.
• Chemical Biology Probes: Employed in the development of fluorinated probes and tags for studying biological mechanisms.
• Cross-Coupling Reactions: Acts as an electrophile in various palladium-catalyzed and other metal-mediated coupling reactions to construct complex architectures.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic synthesis and fluorine chemistry.

Basic Information

Product Name	4-Trifluoromethyl-β-Nitrostyrene
CAS No.	93628-97-8
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	1-(4-(Trifluoromethyl)phenyl)-2-nitroethene; (E)-1-(4-(Trifluoromethyl)phenyl)-2-nitroethene; 4-(Trifluoromethyl)-β-nitrostyrene; 2-Nitro-1-[4-(trifluoromethyl)phenyl]ethene; α-(4-Trifluoromethylphenyl)-β-nitrostyrene; 4-Trifluoromethyl-β-nitrostyrene; p-Trifluoromethyl-β-nitrostyrene
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethyl-β-Nitrostyrene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.