Description

Prostaglandin A1 Ethyl Ester is a chemically modified derivative of the naturally occurring prostaglandin A1, designed to enhance stability and bioavailability for research and development applications. This compound serves as a critical intermediate and reference standard in the study of eicosanoid signaling pathways and their physiological effects. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on cardiovascular, renal, and inflammatory disease models.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel prostaglandin analogs and prodrugs for therapeutic exploration.
• Biochemical Reference Standard: Used for analytical method development, calibration, and quality control in HPLC and LC-MS assays.
• Cell Signaling Studies: Investigation of the biological activities of PGA series prostaglandins on cellular processes like apoptosis and cell cycle regulation.
• Academic & Contract Research: Fundamental research into eicosanoid chemistry, metabolism, and receptor interactions.
• Fine Chemical Synthesis: Serving as a specialized building block for the custom synthesis of high-value, complex organic molecules.

Basic Information

Product Name	Prostaglandin A1 Ethyl Ester
CAS No.	93464-24-5
Molecular Formula	C22H34O5
Molecular Weight	378.51 g/mol
Synonyms	PGA1 Ethyl Ester; Ethyl (5Z,13E)-(9S,11R,15R)-9,11,15-Trihydroxyprosta-5,13-dien-1-oate; 15(R)-PGA1 ethyl ester; Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, ethyl ester, (5Z,9α,11α,13E,15R)-; Ethyl 9,11,15-trihydroxyprosta-5,13-dien-1-oate
EINECS	Contact for details

Quality Control

Our Prostaglandin A1 Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.