Description

Asperlicin is a potent and selective non-peptide cholecystokinin (CCK) antagonist derived from the fungus *Aspergillus alliaceus*. This compound is of significant interest in biochemical and pharmacological research for its ability to competitively inhibit CCK receptors, particularly the CCK-A subtype. It serves as a critical research tool for scientists and organizations in the pharmaceutical, biotechnology, and academic sectors investigating gastrointestinal disorders, satiety signaling, and central nervous system functions.

Application

• Pharmacological Research: A key reference standard and tool compound for studying cholecystokinin receptor (CCK-A and CCK-B) pharmacology and signal transduction pathways.
• Neuroscience Studies: Used in experimental models to explore the role of CCK in anxiety, panic disorders, nociception, and memory processes.
• Gastrointestinal Research: Applied in investigations of CCK-mediated functions such as pancreatic enzyme secretion, gallbladder contraction, and gut motility.
• Drug Discovery: Serves as a lead compound and structural template for the design and development of novel therapeutic agents targeting CCK receptors.
• Biochemical Assays: Utilized as a selective antagonist in receptor binding assays and functional studies to characterize new compounds and elucidate CCK receptor biology.

Basic Information

Product Name	Asperlicin
CAS No.	93413-04-8
Molecular Formula	C33H33N5O6
Molecular Weight	595.65 g/mol
Synonyms	Asperlicin; L-364,718; MK-329; Devazepide; (3S)-1,3-Dihydro-3-[(3S)-3-(1H-indol-3-ylmethyl)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-2H-indol-2-one; 1,4-Benzodiazepine derivative; CCK-A receptor antagonist; Non-peptide cholecystokinin antagonist
EINECS	Contact for details

Quality Control

Our Asperlicin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Keep the material dry and store in a dedicated freezer for biologically active compounds.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.