Description

4-Methyl-3-(trifluoromethyl)benzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its core value lies in the unique reactivity of the aldehyde group and the electron-withdrawing properties imparted by the trifluoromethyl substituent, enabling the construction of complex molecules with tailored properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethyl group for enhanced metabolic stability, lipophilicity, and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials, where the CF3 group influences electronic properties and molecular alignment.
• Functional Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments, with the aldehyde group facilitating condensation reactions to form chromophores.
• Organic Synthesis Building Block: Utilized in various name reactions (e.g., Knoevenagel condensation, reductive amination) to introduce the 4-methyl-3-(trifluoromethyl)phenyl moiety into target molecules.
• Material Science Research: Acts as a monomer or cross-linker in the development of novel polymers and advanced materials with specific thermal or chemical resistance.

Basic Information

Product Name	4-Methyl-3-(trifluoromethyl)benzaldehyde
CAS No.	93249-45-7
Molecular Formula	C9H7F3O
Molecular Weight	188.15 g/mol
Synonyms	3-(Trifluoromethyl)-4-methylbenzaldehyde; 4-Methyl-3-trifluoromethylbenzaldehyde; 3-Trifluoromethyl-p-tolualdehyde; 4-Methyl-α,α,α-trifluoro-m-tolualdehyde; m-Tolualdehyde, 3-(trifluoromethyl)-; Benzaldehyde, 4-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(trifluoromethyl)benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.