Description

Mono-2-o-(p-Toluenesulfonyl)-α-Cyclodextrin is a chemically modified derivative of α-cyclodextrin, featuring a single tosyl group at the 2-O position, which introduces unique properties for molecular encapsulation and selective binding. This modification is critical for creating advanced host-guest complexes with enhanced solubility and stability profiles for challenging substrates. It serves as a valuable intermediate and functional excipient for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular interaction is required.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing more complex, functionalized cyclodextrin derivatives used in drug delivery systems.
• Chiral Separation Agent: Employed in the development of chiral stationary phases for HPLC to separate enantiomers of pharmaceutical compounds.
• Molecular Encapsulation Studies: Used in research to study and improve the solubility, stability, and bioavailability of poorly soluble active ingredients.
• Catalyst and Ligand Support: Serves as a scaffold for attaching catalytic groups, creating novel catalysts for asymmetric synthesis.
• Analytical Chemistry Reference Standard: Provides a high-purity standard for method development and quality control in analytical laboratories.
• Specialty Polymer Modification: Acts as a modifying agent to introduce functional groups into polymers for creating materials with specific molecular recognition properties.

Basic Information

Product Name	Mono-2-o-(p-Toluenesulfonyl)-α-Cyclodextrin
CAS No.	93184-10-2
Molecular Formula	C49H74O37S
Molecular Weight	1239.15 g/mol
Synonyms	2-O-(p-Tolylsulfonyl)-α-cyclodextrin; 2-O-Tosyl-α-cyclodextrin; α-Cyclodextrin 2-O-monotosylate; Mono(2-O-tosyl)-α-cyclodextrin; 6^A-O-(4-Methylbenzenesulfonyl)-α-cyclodextrin; 2-O-(4-Methylphenylsulfonyl)-α-cyclodextrin; α-CD-2-OTs; Ts-α-CD
EINECS	Contact for details

Quality Control

Our Mono-2-o-(p-Toluenesulfonyl)-α-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.