Description

Heptakis(3-o-Acetyl-2,6-Di-o-Methyl)-β-cyclodextrin is a chemically modified cyclodextrin derivative, specifically a peracetylated and permethylated heptasaccharide. This compound is valued for its enhanced solubility in organic solvents and altered cavity properties compared to native β-cyclodextrin, making it a powerful chiral selector and complexing agent. It is primarily required by researchers and manufacturers in the pharmaceutical, analytical chemistry, and agrochemical industries for applications such as chiral separation, drug formulation, and catalysis.

Application

• Chiral Stationary Phase (CSP) in Chromatography: A key component in High-Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC) columns for the enantiomeric separation of racemic pharmaceutical compounds and fine chemicals.
• Chiral Additive in Capillary Electrophoresis (CE): Used as a chiral selector in the background electrolyte to resolve enantiomers in analytical and preparative scales.
• Pharmaceutical Formulation: Acts as a solubility and stability enhancer for poorly water-soluble active pharmaceutical ingredients (APIs) through host-guest inclusion complexation.
• Chemical Synthesis & Catalysis: Serves as a molecular receptor or a phase-transfer catalyst in asymmetric synthesis reactions.
• Analytical Reference Standard: Used as a high-purity standard for method development and validation in analytical laboratories.
• Agrochemical Research: Employed in studies to improve the delivery, stability, or selective activity of pesticides and herbicides.
• Food & Flavor Industry: Potential use for the encapsulation and controlled release of flavors, fragrances, or nutraceuticals.
• Material Science: Component in the development of sensors, membranes, or functionalized nanomaterials.

Basic Information

Item	Details
Product Name	Heptakis(3-o-Acetyl-2,6-Di-o-Methyl)-β-cyclodextrin
CAS No.	131889-29-7
Molecular Formula	C77H112O42
Molecular Weight	1661.7 g/mol
Synonyms	Heptakis(3-O-acetyl-2,6-di-O-methyl)-β-cyclodextrin; 3A-Acetyl-2A,6A-di-O-methyl-β-cyclodextrin (heptakis); 3-Acetyl-2,6-di-O-methyl-β-cyclodextrin; 2,6-Di-O-methyl-3-O-acetyl-β-cyclodextrin; Permethyl 3-acetyl-β-cyclodextrin; Acetylated permethyl-β-cyclodextrin; 3-Ac-2,6-DM-β-CD; DMAB (common abbreviation)
EINECS	Contact for details

Quality Control

Our Heptakis(3-o-Acetyl-2,6-Di-o-Methyl)-β-cyclodextrin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. Standard quality parameters include assay by HPLC, chiral purity, residual solvent analysis, and specific optical rotation. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (as single isomer)
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.