Description

6-Deoxy-6-Cyclo(Histidyl-Leucyl)Cyclodextrin is a chemically modified cyclodextrin derivative, engineered to enhance molecular recognition and binding capabilities for specific guest molecules. This compound is significant for its role in advanced pharmaceutical research, particularly in drug delivery systems and chiral separation processes. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical synthesis industries.

Application

• Chiral Resolution Agent: For the separation of enantiomers in pharmaceutical intermediates and active ingredients.
• Drug Delivery Vehicle: As a functional excipient to improve the solubility, stability, and bioavailability of poorly soluble APIs.
• Catalyst or Ligand Support: In asymmetric synthesis and catalysis due to its modified peptide-cyclodextrin structure.
• Analytical Chemistry: As a stationary phase modifier in HPLC and capillary electrophoresis for complex separations.
• Biomimetic Studies: For modeling enzyme-substrate interactions and studying host-guest chemistry.
• Flavor/Fragrance Encapsulation: In the controlled release of sensitive compounds in food and cosmetic applications.

Basic Information

Product Name	6-Deoxy-6-Cyclo(Histidyl-Leucyl)Cyclodextrin
CAS No.	144363-91-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6-Deoxy-6-(L-histidyl-L-leucyl)cyclodextrin; Cyclo(His-Leu)-6-deoxy-cyclodextrin; Histidyl-Leucyl Modified Cyclodextrin; CD-His-Leu; 6-Cyclo(histidylleucyl)-6-deoxycyclodextrin; Peptide-Conjugated Cyclodextrin; Host-Guest Complexation Agent 144363-91-7
EINECS	Contact for details

Quality Control

Our 6-Deoxy-6-Cyclo(Histidyl-Leucyl)Cyclodextrin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.