Description

4-o-Acetyl-2,5-Anhydro-1,3-Isopropylidene-D-Glucitol is a high-purity, protected carbohydrate derivative that serves as a critical chiral building block and synthetic intermediate. Its value lies in its defined stereochemistry and functional groups, enabling precise chemical transformations in complex synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing nucleoside analogs, antiviral agents, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of nucleoside analogs and antiviral drugs.
• Fine Chemical Synthesis: Used as a protected sugar derivative in multi-step organic synthesis to introduce specific stereocenters.
• Glycochemistry Research: Valuable precursor for constructing complex carbohydrate structures and glycoconjugates in academic and industrial R&D.
• Process Chemistry: Employed in the scalable production of active pharmaceutical ingredients (APIs) requiring specific sugar-based motifs.
• Bioconjugation: Potential use in linker chemistry for drug delivery systems due to its functionalizable hydroxyl groups.

Basic Information

Product Name	4-o-Acetyl-2,5-Anhydro-1,3-Isopropylidene-D-Glucitol
CAS No.	70128-28-8
Molecular Formula	C11H18O6
Molecular Weight	246.26 g/mol
Synonyms	1,2-O-Isopropylidene-5-O-acetyl-α-D-glucofuranose; 5-O-Acetyl-1,2-O-isopropylidene-α-D-glucofuranose; 1,2-O-Isopropylidene-α-D-glucofuranose 5-acetate; 5-Acetyl-1,2-O-isopropylidene-α-D-glucofuranose; D-Glucitol, 4-o-acetyl-2,5-anhydro-1,3-isopropylidene-; 1,2-O-Isopropylidene-α-D-glucofuranose 5-O-acetate
EINECS	Contact for details

Quality Control

Our 4-o-Acetyl-2,5-Anhydro-1,3-Isopropylidene-D-Glucitol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.