Description

2-o-(2-Hydroxypropyl)Cyclomaltoheptaose is a chemically modified cyclodextrin derivative, specifically a hydroxypropyl β-cyclodextrin (HP-β-CD). This compound matters for its superior solubility and ability to form inclusion complexes, enhancing the stability, bioavailability, and delivery of active ingredients. It is a critical excipient needed by formulators in the pharmaceutical, nutraceutical, cosmetic, and agrochemical industries for advanced drug delivery and product stabilization.

Application

• Pharmaceutical Solubilizer & Stabilizer: Enhances the aqueous solubility and chemical stability of poorly soluble active pharmaceutical ingredients (APIs).
• Drug Delivery Systems: Used in parenteral formulations, oral solutions, nasal sprays, and ocular drops to improve bioavailability.
• Cosmetic Ingredient Carrier: Encapsulates fragrances, vitamins, and other actives in creams and lotions for controlled release and reduced irritation.
• Food & Nutraceutical Additive: Improves the stability, shelf-life, and masking of unpleasant tastes in functional food ingredients and supplements.
• Agrochemical Formulations: Increases the solubility and efficacy of pesticides and herbicides.
• Analytical Chemistry: Employed as a chiral selector in capillary electrophoresis and chromatographic separations.
• Catalyst & Reaction Medium: Acts as a host in supramolecular chemistry to modify reaction rates and selectivities.

Basic Information

Product Name	2-o-(2-Hydroxypropyl)Cyclomaltoheptaose
CAS No.	130981-23-6
Molecular Formula	C63H112O42 (Base structure, variable substitution)
Molecular Weight	~1541.5 g/mol (Average, depends on degree of substitution)
Synonyms	Hydroxypropyl-β-cyclodextrin; HP-β-CD; 2-Hydroxypropyl-β-cyclodextrin; Heptakis(2-O-(2-hydroxypropyl))-β-cyclodextrin; (2-Hydroxypropyl)-β-cyclodextrin; Kleptose® HPB; Encapsin® HPB; Hydroxypropyl Betadex
EINECS	Contact for details

Quality Control

Our 2-o-(2-Hydroxypropyl)Cyclomaltoheptaose is manufactured under a quality management system and undergoes rigorous testing to ensure it meets the high standards required for pharmaceutical and food-grade applications. We can supply material compliant with USP-NF, Ph. Eur., and FCC monographs where applicable. A comprehensive Certificate of Analysis (COA) detailing identity, purity, substitution degree, and safety parameters is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent moisture absorption and caking.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Assay (HP-β-CD, by HPLC)	≥ 98.0%
Degree of Substitution (Molar)	0.6 - 1.0 (or as specified)
Water Content (Karl Fischer)	≤ 10.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm
Microbial Limits	Conforms to Ph. Eur./USP
pH (10% solution)	5.0 - 7.5
Specific Rotation	+100° to +105°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.