Description

4,5-Heptadienoic Acid, 7-[3-Hydroxy-2-(3-Hydroxy-4-Phenoxy-1-Butenyl)-5-Oxocyclopentyl]-, Methyl Ester, [1R-[1α,2β(1E,3R*),3α]]- is a high-purity, stereochemically defined prostaglandin intermediate. This compound is critical for the synthesis of advanced pharmaceutical agents, particularly in the development of prostaglandin analogs and other bioactive molecules. It is essential for research and production in pharmaceutical, fine chemical, and advanced organic synthesis laboratories where precise stereochemistry and high purity are non-negotiable for successful outcomes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of prostaglandin analogs and related therapeutic agents.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for creating complex, chiral molecules with specific biological activity.
• Biochemical Research: Serves as a reference standard or precursor in studies involving eicosanoid pathways and receptor binding.
• Process Development: Employed in scaling up and optimizing synthetic routes for prostaglandin-based active pharmaceutical ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Detail
Product Name	4,5-Heptadienoic Acid, 7-[3-Hydroxy-2-(3-Hydroxy-4-Phenoxy-1-Butenyl)-5-Oxocyclopentyl]-, Methyl Ester, [1R-[1α,2β(1E,3R*),3α]]-
CAS No.	93000-00-1
Molecular Formula	C23H28O6
Molecular Weight	400.47 g/mol
Synonyms	Methyl 7-[3-Hydroxy-2-[(1E,3R)-3-Hydroxy-4-phenoxy-1-buten-1-yl]-5-oxocyclopentyl]-4,5-heptadienoate; Prostaglandin F2α Methyl Ester Intermediate; (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; 9,11,15-Trihydroxy-17-phenoxy-18,19,20-trinorprosta-5,13-dien-1-oic Acid Methyl Ester; PGF2α Phenoxy Methyl Ester Derivative; 16-Phenoxy Tetranor PGF2α Methyl Ester
EINECS	Contact for details

Quality Control

Our 4,5-Heptadienoic Acid, 7-[3-Hydroxy-2-(3-Hydroxy-4-Phenoxy-1-Butenyl)-5-Oxocyclopentyl]-, Methyl Ester, [1R-[1α,2β(1E,3R*),3α]]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and isomeric purity suitable for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Isomeric Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.