Description

Bulgecin A is a specialized β-lactamase inhibitor compound with significant biochemical research applications. Its primary value lies in its ability to potentiate the activity of β-lactam antibiotics against certain resistant bacterial strains, making it a critical tool for studying bacterial resistance mechanisms. This product is essential for researchers and developers in the pharmaceutical, biotechnology, and academic sectors focused on antimicrobial discovery and enzymology.

Application

• Biochemical Research: Used as a potent inhibitor of specific bacterial lytic transglycosylases and β-lactamases in enzymatic studies.
• Antibiotic Synergy Studies: Employed in research to investigate and enhance the efficacy of β-lactam antibiotics against resistant pathogens.
• Microbiology & Pharmacology: A key reagent for studying bacterial cell wall biosynthesis, degradation pathways, and resistance development.
• Drug Discovery Platforms: Serves as a reference compound and biochemical probe in high-throughput screening assays for novel antimicrobial agents.
• Academic & Institutional Labs: Utilized in university and research institute settings for fundamental research into bacterial physiology and antibiotic action.

Basic Information

Product Name	Bulgecin A
CAS No.	92953-54-3
Molecular Formula	C14H26N4O9
Molecular Weight	394.38 g/mol
Synonyms	Bulgecin A; (2R,3S,4R,5S)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxy-2-[[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]amino]-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide; Antibiotic bulgecin A; Lytic transglycosylase inhibitor; β-Lactamase enhancer
EINECS	Contact for details

Quality Control

Our Bulgecin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the container to reach room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.