Description

2,4,5-Trimethylbenzenesulfonyl Chloride (Saltdata: Free) is a high-purity sulfonyl chloride derivative, a crucial reagent in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation and coupling agent, enabling the construction of complex molecules with high selectivity and yield. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemical intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the production of sulfonamide-based drugs and other active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a protecting group reagent for amino acids during solid-phase and solution-phase peptide synthesis.
• Polymer & Material Science: Employed as a monomer or modifying agent to create specialty polymers with specific sulfonyl functionalities.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of sulfonated dyes and colorants.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed coupling reactions to form carbon-sulfur and carbon-carbon bonds.

Basic Information

Product Name	2,4,5-Trimethylbenzenesulfonyl Chloride (Saltdata: Free)
CAS No.	92890-80-7
Molecular Formula	C9H11ClO2S
Molecular Weight	218.70 g/mol
Synonyms	2,4,5-Trimethylbenzenesulfonyl chloride; Pseudocumene-2-sulfonyl chloride; 2,4,5-Trimethylphenylsulfonyl chloride; 1,2,4-Trimethyl-5-sulfonylchlorobenzene; 5-Chlorosulfonyl-1,2,4-trimethylbenzene; TMBSC; Pseudocumenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,4,5-Trimethylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.