Description

17(S)-Hdohe is a high-purity, stereospecific hydroxy fatty acid derivative of significant interest in advanced biochemical research and development. This compound serves as a crucial synthetic intermediate and reference standard for studying lipid metabolism, inflammation pathways, and specialized pro-resolving mediators (SPMs). It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and academic institutions focused on developing novel therapeutics and diagnostic tools related to eicosanoid biology.

Application

• Pharmaceutical Research: Key intermediate in the synthesis of bioactive lipid mediators and novel anti-inflammatory drug candidates.
• Biochemical Reference Standard: Used as an analytical standard in HPLC, LC-MS, and GC-MS for the quantification and identification of related hydroxy fatty acids in complex biological matrices.
• Metabolic Pathway Studies: Essential tool for investigating the biosynthesis and function of oxylipins and related signaling molecules in cell culture and in vivo models.
• Academic & Contract Research: Employed in universities and CROs for fundamental research on eicosanoid chemistry, enzymology, and receptor interactions.
• Diagnostic Development: Potential use in developing assays and kits for monitoring specific lipid mediators associated with disease states.

Basic Information

Product Name	17(S)-Hdohe
CAS No.	92693-03-3
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	17(S)-HDoHE; 17(S)-Hydroxydocosahexaenoic Acid; (5Z,8Z,11Z,13E,15E,19Z)-17-Hydroxydocosa-5,8,11,13,15,19-hexaenoic Acid; 17S-HDoHE; 17(S)-HDHA; 17S-Hydroxy-4,7,10,13,15,19-docosahexaenoic Acid; 17(S)-HDoHE Standard; 17S-HDoHE Reference Material
EINECS	Contact for details

Quality Control

Every batch of 17(S)-Hdohe is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing lot-specific results from HPLC, NMR, and MS are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98% (17S-isomer)
Water Content (KF)	≤ 0.5%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.