Description

o-Tolyl-Methanesulfonyl Chloride is a specialized organic sulfonyl chloride derivative, a key building block in advanced chemical synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the o-tolylmethanesulfonyl moiety to create novel compounds with tailored properties. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of potential drug candidates, particularly in creating sulfonamide-based active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the sulfonyl group can enhance biological activity.
• Material Science Research: Employed in the production of specialty polymers, dyes, and photoinitiators where specific sulfonated structures are required.
• Chemical Biology & Proteomics: Acts as a versatile tool for protein labeling, modification, and the study of enzyme inhibition mechanisms.
• Custom Synthesis & Contract Manufacturing: Serves as a foundational block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	o-Tolyl-Methanesulfonyl Chloride
CAS No.	92614-55-6
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	2-Methylbenzenesulfonyl Chloride; o-Toluenesulfonyl Chloride; 2-Tolylmethanesulfonyl Chloride; (2-Methylphenyl)methanesulfonyl Chloride; α-Toluenesulfonyl Chloride; o-Tolylsulfonyl Chloride; 2-Methylbenzylsulfonyl Chloride; o-Methylbenzenesulfonyl Chloride
EINECS	Contact for details

Quality Control

Our o-Tolyl-Methanesulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to relevant ISO guidelines and can support documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.