Description

Saframycin H CAS NO 92569-01-2 is a potent ansamycin-class antibiotic compound. This molecule is valued for its significant biological activity, making it a crucial intermediate and reference standard in advanced research. It is primarily sought by pharmaceutical R&D laboratories and biotechnology companies engaged in the development of novel anti-infective and anticancer therapeutics.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and building block in the synthesis and study of novel antibiotic agents.
• Anticancer Agent Discovery: Investigated for its cytotoxic properties and potential mechanisms of action against various cancer cell lines.
• Microbiological Studies: Used as a tool compound to study bacterial resistance mechanisms and the structure-activity relationships of ansamycins.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) campaigns to identify new targets or modulators of biological pathways.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and pharmacology.
• GMP Intermediate: Potential use as a controlled intermediate in the synthesis of active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Saframycin H
CAS No.	92569-01-2
Molecular Formula	C28H30N4O7
Molecular Weight	534.56 g/mol
Synonyms	Saframycin H; Antibiotic C-15003PH; C-15003PH; NSC 339638; (1S,13S,14R,15S,16R,28S,29S,30R)-15,16-Dimethoxy-14,29-dimethyl-7,22-dioxo-2,6,21,25-tetraoxa-8,23-diazaheptacyclo[23.7.1.13,7.19,13.117,21.05,31.027,32]tritriaconta-3,5(31),9,11,17,19,26,32-octaene-28-carboxamide; 1H-Pyrrolo[2,1-c][1,4]benzodiazepine-6-carboxamide, 1,2,3,12-tetrahydro-8,9-dimethoxy-2,12-dimethyl-7H-pyrido[1',2':1,2]pyrrolo[3,4-f][1,4]diazacyclopentadecine-5,10,14(13H)-trione deriv.
EINECS	Contact for details

Quality Control

Our Saframycin H is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to brownish powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.