Description

6-Desmethylsulfadimethoxine is a key intermediate and metabolite in the synthesis and analysis of sulfadimethoxine, a sulfonamide antibiotic. This compound is of significant importance for pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and the production of analytical reference standards. It is primarily needed by manufacturers and research institutions in the pharmaceutical, veterinary medicine, and analytical chemistry sectors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of sulfadimethoxine and related sulfonamide antibiotics.
• Metabolite Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for drug metabolism and pharmacokinetic (DMPK) studies.
• Veterinary Drug Research: Employed in the development and quality control of veterinary medicinal products containing sulfadimethoxine.
• Analytical Chemistry: Serves as a high-purity standard for HPLC, LC-MS, and other chromatographic methods to quantify sulfadimethoxine and its metabolites in various matrices.
• Biochemical Research: Utilized in studies investigating the mode of action, resistance mechanisms, and environmental fate of sulfonamide drugs.

Basic Information

Product Name	6-Desmethylsulfadimethoxine
CAS No.	92545-61-4
Molecular Formula	C₁₁H₁₂N₄O₄S
Molecular Weight	296.30 g/mol
Synonyms	4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide; Sulfadimethoxine Impurity C; Sulfadimethoxine Metabolite; N1-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide; 6-Desmethyl Sulfadimethoxine; 4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
EINECS	Contact for details

Quality Control

Our 6-Desmethylsulfadimethoxine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.