Description

(-) Anatoxin-A Fumarate CAS NO 92142-32-0 is a high-purity, stable fumarate salt form of the potent neurotoxin and nicotinic acetylcholine receptor agonist, (-)-Anatoxin-A. This compound is of critical importance for advanced neuroscience and pharmacological research, serving as a highly selective molecular tool. It is primarily utilized by research institutions and pharmaceutical R&D departments for receptor binding studies, neurotoxicity research, and the development of novel therapeutic agents targeting the cholinergic system.

Application

• Neuroscience Research: As a potent and selective agonist for nicotinic acetylcholine receptors (nAChRs) in electrophysiology and neuropharmacology studies.
• Receptor Binding Assays: Used as a high-affinity ligand in competitive binding experiments to characterize receptor subtypes and screen for potential antagonists.
• Toxicology & Safety Assessment: Employed as a reference standard in environmental and forensic toxicology to study cyanobacterial (blue-green algae) poisoning.
• Drug Discovery & Development: Serves as a key pharmacological tool in the research and development of new drugs for neurological disorders, including Alzheimer's disease and nicotine addiction.
• Biochemical Pathway Analysis: Used to investigate cholinergic signaling pathways and the mechanisms of neuronal excitation and desensitization.
• Academic & Institutional Research: Fundamental research in universities and government labs focusing on neurochemistry, ion channel function, and toxin mechanisms of action.

Basic Information

Item	Details
Product Name	(-) Anatoxin-A Fumarate
CAS No.	92142-32-0
Molecular Formula	C15H21NO6
Molecular Weight	311.33 g/mol
Synonyms	(-)-Anatoxin-A Fumarate; Anatoxin A Fumarate; Very Fast Death Factor Fumarate; VFDF Fumarate; (1R,6S)-1-(9-Azabicyclo[4.2.1]non-2-en-2-yl)ethan-1-one fumarate; FAA; 2-Acetyl-9-azabicyclo[4.2.1]non-2-ene fumarate
EINECS	Contact for details

Quality Control

Our (-) Anatoxin-A Fumarate is manufactured under strict quality management protocols to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and MS. We adhere to relevant guidelines for research chemicals to guarantee product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.